c-kit and bcl-2 Are Not Useful Markers in Differentiating Adenoid Cystic Carcinoma from Polymorphous Low-Grade Adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Diagnostic utility of C-kit protein (CD117) expression in differentiating adenoid cystic carcinoma and polymorphous low grade Adenocarcinoma
Background & Objective To evaluate usefulness of immunohistochemical marker C-kit (CD117) in differentiating Adenoid cystic carcinoma (AdCC) from Polymorphous low-grade adenocarcinoma (PLGA) in patients of salivary gland carcinomas. AdCC is a malignant salivary gland neoplasm with poor prognosis. PLGA is a salivary gland malignancy with indolent growth pattern. Differentiating between the two e...
متن کاملComparison of immunohistochemical markers between adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma.
Adenoid cystic carcinoma (AdCC) and polymorphous low-grade adenocarcinoma (PLGA) have several common histological and clinicopathological features that may create diagnostic difficulties. In this study, 10 AdCCs, 8 PLGAs, and 5 normal minor salivary glands as a control group were selected. Sections prepared from each tumor were stained using the streptavidin-biotin system for seven marker antig...
متن کاملC-kit expression in the salivary gland neoplasms adenoid cystic carcinoma, polymorphous low-grade adenocarcinoma, and monomorphic adenoma.
OBJECTIVE Differentiating between adenoid cystic carcinomas (ACCs), polymorphous low-grade adenocarcinomas (PLGAs), and the monomorphic adenomas (including canalicular adenomas, trabecular adenomas, and basal cell adenomas) can present a diagnostic challenge, especially when examining tissue obtained from small incisional or fragmented biopsies. Recent studies have revealed that overexpression ...
متن کاملevaluation of adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma by immunohistochemistry
background and aim: salivary gland tumors classification continuously undergoes alternations, especially in the recent years. this study used immunohistochemical markers for distinguishing between polymorphous low-grade adenocarcinoma (plga) and adenocarcinoma carcinoma (adcc) which have several overlapping histological and clinical features. materials & methods: ten adcc and eight plga with fi...
متن کاملSilver staining efficiency in differential diagnosis of adenoid cystic carcinoma (ACC) from polymorpheus low-grade adenocarcinoma (PLGA)
Objectives The aim of this study is finding a practical and easy way to differentiate, between two malignant tumors Adenoid Cystic Carcinoma (ACC) and Polymorphous Low-grade Adeno Carcinoma (PLGA) histologically. In this regard, We proposed silver nitrate staining (AgNOR). Methods In this cross-sectional study, 30 parrafin-embedded blocks of ACC and 9 paraffin-embedded b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ISRN Pathology
سال: 2011
ISSN: 2090-570X,2090-5718
DOI: 10.5402/2011/415614